Senior Bioinformatics Engineer 


DNA Science | San Francisco, California, United States

Senior Bioinformatics Engineer

  • San Francisco, California, United States
  • DNA Science
  • Full-time

About Ancestry:

When you join Ancestry, you join a human-centered company where every person’s story is important. We believe that by discovering the struggles and triumphs of our past, we can foster deeper bonds and more meaningful connections among families and communities. Our talented team of scientists, engineers, genealogists, historians, and storytellers is dedicated to empowering customers around the world from all backgrounds on their journeys of personal discovery. 


With more than 30+ billion digitized global historical records, 100+ million family trees, and 20+ million people in our growing AncestryDNA database, Ancestry helps customers discover their family story and gain a new level of understanding about their lives. Passionate about dedicating your work to enriching people’s lives? You belong at Ancestry.


AncestryDNA is looking for a Senior Data Engineer to join our Bioinformatics team. Reporting to the Bioinformatics Manager, this individual will enable our Research Scientists in the AWS cloud. The team coordinates with other teams within AncestryDNA, and teams across Ancestry. This team provides an essential role within Ancestry to support the flow of information to drive scientific innovation. 

What You'll Do:

  • Streamline manual processes to improve quality, reproducibility, and access to data.
  • Build and maintain data systems and pipelines. 
  • Harmonize and transform raw information from different sources to create consistent and machine-readable formats.
  • Develop and test architectures that enable data extraction and transformation for predictive or prescriptive modeling

Who You Are:

  • Previous experience as a data engineer or in a similar role
  • Technical expertise with data models, data mining, and segmentation techniques
  • Knowledge of programming languages (Python strongly preferred)
  • Hands-on experience with complex SQL queries and database design
  • Experience developing interactive visualization tools to support non-technical stakeholders (e.g., RShiny, Streamlit, Tableau, web-based applications)
  • Experienced with Spark/Hadoop experience for big data analytics

Required Skills and Qualifications:

  • Master’s degree in stats, physics, computer science, or related discipline
  • 3 or more years of experience with Python, SQL, and interactive data visualization/exploration tools
  • Experience using Python to automate tasks
  • Experience with Bash, Linux administration
  • Communication skills, especially explaining technical concepts to non-technical business leaders
  • Comfort working in a dynamic, research-oriented team with concurrent projects
  • Familiarity with the AWS ecosystem
  • Knowledge of infrastructure tools like Terraform and AWS CloudFormation
  • Experience working with biological data/scientists
  • familiarity with workflow orchestration tools/languages to automate tasks and deploy pipelines

Additional Information:

Ancestry is an Equal Opportunity Employer that makes employment decisions without regard to race, color, religious creed, national origin, ancestry, sex, pregnancy, sexual orientation, gender, gender identity, gender expression, age, mental or physical disability, medical condition, military or veteran status, citizenship, marital status, genetic information, or any other characteristic protected by applicable law. In addition, Ancestry will provide reasonable accommodations for qualified individuals with disabilities.


All job offers are contingent on a background check screen that complies with applicable law.  For San Francisco office candidates, pursuant to the San Francisco Fair Chance Ordinance, Ancestry will consider for employment qualified applicants with arrest and conviction records.  


Ancestry is not accepting unsolicited assistance from search firms for this employment opportunity. All resumes submitted by search firms to any employee at Ancestry via-email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Ancestry. No fee will be paid in the event the candidate is hired by Ancestry as a result of the referral or through other means.


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